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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPLAH
All Species:
23.94
Human Site:
Y677
Identified Species:
47.88
UniProt:
O14841
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14841
NP_060040.1
1288
137457
Y677
G
Y
Q
E
T
P
V
Y
L
L
A
E
L
G
Y
Chimpanzee
Pan troglodytes
XP_528261
1212
130154
G643
V
R
G
T
G
R
S
G
L
R
L
E
D
A
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539206
1379
147579
Y774
G
Y
Q
E
T
P
V
Y
L
L
G
E
L
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K010
1288
137593
Y677
G
Y
Q
E
T
P
V
Y
L
L
G
E
L
G
Y
Rat
Rattus norvegicus
P97608
1288
137702
Y677
G
Y
Q
E
T
P
V
Y
L
L
G
E
L
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521030
1300
139318
Y689
G
Y
Q
E
T
P
V
Y
V
L
E
E
L
G
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611675
1294
139594
Y680
G
A
F
D
S
P
I
Y
L
T
K
N
L
L
A
Honey Bee
Apis mellifera
XP_001121487
1287
139635
Y677
G
Y
Q
E
T
K
V
Y
Q
L
R
S
L
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794494
1307
142838
Y686
G
L
L
D
T
A
I
Y
L
L
D
D
L
S
S
Poplar Tree
Populus trichocarpa
XP_002305860
1269
137853
L683
L
D
T
P
L
Y
K
L
D
N
L
G
C
G
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIZ7
1266
137512
L679
H
D
T
P
L
F
K
L
E
N
L
G
F
G
H
Baker's Yeast
Sacchar. cerevisiae
P28273
1286
140409
D690
T
A
V
F
K
I
D
D
L
P
A
G
T
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
N.A.
69.4
N.A.
92.5
93.9
N.A.
80.2
N.A.
N.A.
N.A.
N.A.
61.2
65
N.A.
64.1
Protein Similarity:
100
93.1
N.A.
74
N.A.
95.6
96.1
N.A.
87.2
N.A.
N.A.
N.A.
N.A.
74.5
76.9
N.A.
76.1
P-Site Identity:
100
13.3
N.A.
80
N.A.
93.3
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
33.3
60
N.A.
40
P-Site Similarity:
100
13.3
N.A.
80
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
53.3
60
N.A.
60
Percent
Protein Identity:
57.2
N.A.
N.A.
56.8
49
N.A.
Protein Similarity:
70.9
N.A.
N.A.
71.2
66
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
9
0
0
0
0
17
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% C
% Asp:
0
17
0
17
0
0
9
9
9
0
9
9
9
0
0
% D
% Glu:
0
0
0
50
0
0
0
0
9
0
9
50
0
0
0
% E
% Phe:
0
0
9
9
0
9
0
0
0
0
0
0
9
0
0
% F
% Gly:
67
0
9
0
9
0
0
9
0
0
25
25
0
50
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
0
0
0
9
17
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
0
0
9
9
17
0
0
0
9
0
0
0
0
% K
% Leu:
9
9
9
0
17
0
0
17
67
59
25
0
67
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
17
0
9
0
0
0
% N
% Pro:
0
0
0
17
0
50
0
0
0
9
0
0
0
0
9
% P
% Gln:
0
0
50
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
9
0
0
0
9
9
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
9
0
0
0
0
9
0
17
17
% S
% Thr:
9
0
17
9
59
0
0
0
0
9
0
0
9
0
0
% T
% Val:
9
0
9
0
0
0
50
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
9
0
67
0
0
0
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _